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Location of the complement factor H binding site on streptococcal M6 protein.

The surface M protein of group A streptococci binds factor H, a regulatory protein of the alternative complement pathway, which may contribute to the antiphagocytic activity of the M molecules. To locate the factor H binding domain in the alpha-helical coiled-coil structure of the M molecule, the M...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Fischetti, V A, Horstmann, R D, Pancholi, V
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1995
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172971/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7806351/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.1.149-153.1995
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