Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos

Dbl-homology guanine nucleotide exchange factors (DH-GEFs) regulate actin cytoskeletal reorganization, cell adhesion, and gene transcription via activation of Rho GTPases. However, little is known about the physiological role of mammalian DH-GEFs during development. The DH-GEF family member Trio is...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	O'Brien, Stephen P., Seipel, Katja, Medley, Quintus G., Bronson, Roderick, Segal, Rosalind, Streuli, Michel
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050238/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.22.12074
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