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Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications.

Methicillin resistance in staphylococci is determined by mec, composed of 50 kb or more of DNA found only in methicillin-resistant strains. mec contains mecA, the gene for penicillin-binding protein 2a (PBP 2a); mecI and mecR1, regulatory genes controlling mecA expression; and numerous other element...

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Dettagli Bibliografici
Pubblicato in:Clin Microbiol Rev
Autore principale: Chambers, H F
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1997
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172944/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9336672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/cmr.10.4.781
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