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Bile acid metabolism by fresh human colonic contents: a comparison of caecal versus faecal samples

BACKGROUND—Deoxycholic acid (DCA), implicated in the pathogenesis of gall stones and colorectal cancer, is mainly formed by bacterial deconjugation (cholylglycine hydrolase (CGH)) and 7α-dehydroxylation (7α-dehydroxylase (7α-DH)) of conjugated cholic acid (CA) in the caecum/proximal colon. Despite t...

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Detalhes bibliográficos
Main Authors: Thomas, L, Veysey, M, French, G, Hylemon, P, Murphy, G, Dowling, R
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728526/
https://ncbi.nlm.nih.gov/pubmed/11709519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.49.6.835
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