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Allelic variation at the interleukin 1β gene is associated with decreased bone mass in patients with inflammatory bowel diseases
BACKGROUND—Interleukin 1β (IL-1β) and its natural antagonist have been implicated in the pathogenesis of inflammatory bowel disease (IBD). Both cytokines influence bone formation. IL-1β stimulates osteoclast activity while interleukin 1 receptor antagonist (IL-1ra) enhances bone formation. AIMS—To d...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1728500/ https://ncbi.nlm.nih.gov/pubmed/11600466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.49.5.644 |
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