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Association of the tumour necrosis factor α −308 but not the interleukin 10 −627 promoter polymorphism with genetic susceptibility to primary sclerosing cholangitis

BACKGROUND AND AIMS—Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown aetiology. Abnormalities in immune regulation and genetic associations suggest that PSC is an immune mediated disease. Several polymorphisms within the tumour necrosis factor α (TNF-α) and inte...

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書誌詳細
主要な著者: Mitchell, S, Grove, J, Spurkland, A, Boberg, K, Fleming, K, Day, C, Schrumpf, E, Chapman, R, the, E
フォーマット: Artigo
言語:Inglês
出版事項: 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728404/
https://ncbi.nlm.nih.gov/pubmed/11454808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.49.2.288
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