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Conservation of the cag pathogenicity island is associated with vacA alleles and gastroduodenal disease in South African Helicobacter pylori isolates

BACKGROUND—The development of clinically significant disease in South Africa is associated with the vacuolating cytotoxin gene (vacA) s1 genotype but not with the presence of the cytotoxin associated gene cagA. cagA occurs in >95% of South African isolates and is a variable marker for the entire...

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Bibliographic Details
Main Authors: Kidd, M, Lastovica, A, Atherton, J, Louw, J
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728366/
https://ncbi.nlm.nih.gov/pubmed/11413104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.49.1.11
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