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Gastrointestinal cell proliferation and crypt fission are separate but complementary means of increasing tissue mass following infusion of epidermal growth factor in rats

BACKGROUND AND AIMS—Epidermal growth factor (EGF) is a potent mitogen for the gastrointestinal tract and also influences the number of new crypts formed by crypt fission. The time course of these events and possible linkage between these two complementary mechanisms is however poorly understood. We...

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Autori principali: Berlanga-Acosta, J, Playford, R, Mandir, N, Goodlad, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728321/
https://ncbi.nlm.nih.gov/pubmed/11358899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.48.6.803
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