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Expression and penetrance of the hereditary pancreatitis phenotype in monozygotic twins

BACKGROUND—Hereditary pancreatitis (HP) is a rare autosomal dominant disorder with variable expression and an overall lifetime penetrance of 80%. We hypothesised that (1) monozygotic twins within similar environments would develop the typical signs of HP at a similar age, and (2) if penetrance were...

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Detalhes bibliográficos
Main Authors: Amann, S, Gates, L, Aston, C, Pandya, A, Whitcomb, D
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728254/
https://ncbi.nlm.nih.gov/pubmed/11247900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.48.4.542
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