Structure-activity relationships of fluorinated nucleoside analogs and their synergistic effect in combination with phosphonoformate against human immunodeficiency virus type 1.
One hundred nucleoside analogs with fluorine substitutions at various positions on the pentose ring were evaluated for inhibitory activity against human immunodeficiency virus type 1 (HIV-1). Nine compounds emerged as inhibitors of HIV-1 replication, with various degrees of selectivity; the most act...
שמור ב:
| הוצא לאור ב: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
1989
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2533474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.12.2083 |
| תגים: |
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