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Colonic crypt cell proliferation state assessed by whole crypt microdissection in sporadic neoplasia and familial adenomatous polyposis

BACKGROUND—It has yet to be established whether proliferative activity in the macroscopically normal colonic mucosa is causally correlated with neoplastic risk. Measurement of proliferative activity in human subjects is of necessity usually undertaken using indirect methods with inherent limitations...

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Autors principals: Mills, S, Mathers, J, Chapman, P, Burn, J, Gunn, A
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728170/
https://ncbi.nlm.nih.gov/pubmed/11115821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.48.1.41
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