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Oral glutamine in the prevention of fluorouracil induced intestinal toxicity: a double blind, placebo controlled, randomised trial

BACKGROUND—5-Fluorouracil (FU) in association with folinic acid (FA) is the most frequently used chemotherapeutic agent in colorectal cancer but it often causes diarrhoea. Animal and human studies suggest that glutamine stimulates intestinal mucosal growth.
AIM—To determine if oral glutamine prevent...

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Main Authors: Daniele, B, Perrone, F, Gallo, C, Pignata, S, De Martino, S, De Vivo, R, Barletta, E, Tambaro, R, Abbiati, R, D'Agostino, L
Formato: Artigo
Idioma:Inglês
Publicado: 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728161/
https://ncbi.nlm.nih.gov/pubmed/11115819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.48.1.28
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