Radiation induced cytochrome c release causes loss of rat colonic fluid absorption by damage to crypts and pericryptal myofibroblasts

BACKGROUND—Therapeutic or accidental exposure to radiation commonly causes gastrointestinal disturbances, including diarrhoea. Rats subjected to whole body ionising radiation at a dose of 8 Gy lose their capacity to absorb fluid via the descending colon after four days. After seven days, fluid absor...

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Main Authors: Thiagarajah, J, Gourmelon, P, Griffiths, N, Lebrun, F, Naftalin, R, Pedley, K
Formato: Artigo
Idioma:Inglês
Publicado: 2000
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728123/
https://ncbi.nlm.nih.gov/pubmed/11034584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.5.675
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