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HFE gene mutation (C282Y) and phenotypic expression among a hospitalised population in a high prevalence area of haemochromatosis

BACKGROUND—Previous studies have shown that up to 0.5% of the Caucasian population is homozygous for the HFE gene C282Y mutation. High prevalence values have been reported in Northern Europe. To what extent the presence of this mutation is associated with overt clinical haemochromatosis is unclear.
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Detalhes bibliográficos
Main Authors: Distante, S, Berg, J, Lande, K, Haug, E, Bell, H
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728064/
https://ncbi.nlm.nih.gov/pubmed/10986220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.4.575
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