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DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer

BACKGROUND AND AIM—Hereditary non-polyposis colorectal cancer (HNPCC), as its name implies, is associated with few adenomas, and the early evolution of colorectal neoplasia is poorly understood. In this study our aim was to clarify the genetic profiles of benign polyps in subjects with HNPCC using a...

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Détails bibliographiques
Auteurs principaux: Iino, H, Simms, L, Young, J, Arnold, J, Winship, I, Webb, S, Furlong, K, Leggett, B, Jass, J
Format: Artigo
Langue:Inglês
Publié: 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727981/
https://ncbi.nlm.nih.gov/pubmed/10861262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.1.37
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