DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer

BACKGROUND AND AIM—Hereditary non-polyposis colorectal cancer (HNPCC), as its name implies, is associated with few adenomas, and the early evolution of colorectal neoplasia is poorly understood. In this study our aim was to clarify the genetic profiles of benign polyps in subjects with HNPCC using a...

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Detalhes bibliográficos
Main Authors: Iino, H, Simms, L, Young, J, Arnold, J, Winship, I, Webb, S, Furlong, K, Leggett, B, Jass, J
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727981/
https://ncbi.nlm.nih.gov/pubmed/10861262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.1.37
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