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Combined antibody and ganciclovir treatment of murine cytomegalovirus-infected normal and immunosuppressed BALB/c mice.

The efficacy of treatment with ganciclovir (DHPG) and antibody activity-containing ascitic fluid (AF) separately and in combination was studied in normal and immunosuppressed BALB/c mice challenged intraperitoneally with a lethal dose (10(6) PFU) of murine cytomegalovirus (CMV). With combination the...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Rubin, R H, Lynch, P, Pasternack, M S, Schoenfeld, D, Medearis, D N
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1989
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172798/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2558616/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.11.1975
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