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Cytotoxic T lymphocyte responses and CTL epitope escape mutation in HBsAg, anti-HBe positive individuals

BACKGROUND/AIMS—Clearance of hepatitis B virus (HBV) is characterised by a strong cytotoxic T cell response. Persistence of HBV in chronic hepatitis B carriers may be related to failure of this response. The aim of this study was to determine whether HLA class I restricted cytotoxic T lymphocyte (CT...

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Detalhes bibliográficos
Main Authors: Khakoo, S, Ling, R, Scott, I, Dodi, A, Harrison, T, Dusheiko, G, Madrigal, J
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727966/
https://ncbi.nlm.nih.gov/pubmed/10861276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.1.137
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