Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease

BACKGROUND—Degradation of the extracellular matrix and ulceration of the mucosa are major features of inflammatory bowel disease (IBD). One of the most important enzymes in degrading the matrix and produced in excess by cytokine activated stromal cells, is stromelysin-1. The activity of stromelysin-...

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Hlavní autoři: Heuschkel, R, MacDonald, T, Monteleone, G, Bajaj-Elliott, M, Smith, J, Pender, S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727949/
https://ncbi.nlm.nih.gov/pubmed/10861265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.1.57
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