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Butyrate and trichostatin A effects on the proliferation/differentiation of human intestinal epithelial cells: induction of cyclin D3 and p21 expression

BACKGROUND—Sodium butyrate, a product of colonic bacterial fermentation, is able to inhibit cell proliferation and to stimulate cell differentiation of colonic epithelial cell lines. It has been proposed that these cellular effects could be linked to its ability to cause hyperacetylation of histone...

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Detalhes bibliográficos
Main Authors: Siavoshian, S, Segain, J, Kornprobst, M, Bonnet, C, Cherbut, C, Galmiche, J, Blottiere, H
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727889/
https://ncbi.nlm.nih.gov/pubmed/10716680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.46.4.507
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