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Liver/kidney microsomal antibody type 1 targets CYP2D6 on hepatocyte plasma membrane
BACKGROUND—Liver/kidney microsomal antibody type 1 (LKM1) is the marker of type 2 autoimmune hepatitis (AIH) and is detected in up to 6% of patients with hepatitis C virus (HCV) infection. It recognises linear and conformational epitopes of cytochrome P450IID6 (CYP2D6) and may have liver damaging ac...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1727874/ https://ncbi.nlm.nih.gov/pubmed/10716687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.46.4.553 |
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