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Polynucleotide phosphorylase functions both as a 3′ → 5′ exonuclease and a poly(A) polymerase in Escherichia coli

In vitro, polynucleotide phosphorylase of Escherichia coli can both synthesize RNA by using nucleotide diphosphates as precursors and exonucleolytically degrade RNA in the presence of inorganic phosphate. However, because of the high in vivo concentration of inorganic phosphate in exponentially grow...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Mohanty, Bijoy K., Kushner, Sidney R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17278/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11035800/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220295997
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