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Somatostatin plus isosorbide 5-mononitrate versus somatostatin in the control of acute gastro-oesophageal variceal bleeding: a double blind, randomised, placebo controlled clinical trial

BACKGROUND—Variceal bleeding is a severe complication of portal hypertension. Somatostatin reduces portal pressure by decreasing splanchnic blood flow, and nitrates by diminishing intrahepatic resistance. Experimental studies have shown that the combination of somatostatin and nitrates has an additi...

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Detalhes bibliográficos
Main Authors: Junquera, F, Lopez-Talavera, J, Mearin, F, Saperas, E, Videla, S, Armengol, J, Esteban, R, Malagelada, J
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727780/
https://ncbi.nlm.nih.gov/pubmed/10601068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.46.1.127
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