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Randomised controlled trial shows that glyceryl trinitrate heals anal fissures, higher doses are not more effective, and there is a high recurrence rate

BACKGROUND—Topical application of glyceryl trinitrate (GTN) ointment heals chronic anal fissures, providing an alternative to the traditional first line treatment of surgical sphincterotomy. 
AIMS—To determine the most effective dose of topical GTN for treatment of chronic anal fissures and to asses...

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Detalhes bibliográficos
Main Authors: Carapeti, E, Kamm, M, McDonald, P, Chadwick, S, Melville, D, Phillips, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727506/
https://ncbi.nlm.nih.gov/pubmed/10205213
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