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Cisplatin impairs fluid and electrolyte absorption in rat small intestine: a role for 5-hydroxytryptamine

Background—The antineoplastic drug cisplatin has been widely used for the treatment of cancer in humans but its use has been limited by vomiting and diarrhoea. Cisplatin releases 5-hydroxytryptamine into the gut which is thought to be the major mediator of cisplatin induced vomiting. 
Aim—To determi...

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Detalhes bibliográficos
Main Authors: Bearcroft, C, Domizio, P, Mourad, F, Andre, E, Farthing, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1727387/
https://ncbi.nlm.nih.gov/pubmed/9895375
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