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Mechanism of penicillin killing in the absence of bacterial lysis.

Exposure of group A streptococci (a nonlytic-death phenotype) to benzylpenicillin (penicillin G) produced a dose-dependent, rapid, and extensive hydrolysis of total cellular RNA, with the subsequent loss of hydrolysis products from the cell. This loss of RNA correlated well with loss of viability an...

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Bibliografiske detaljer
Main Authors: McDowell, T D, Reed, K E
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC172737/
https://ncbi.nlm.nih.gov/pubmed/2480078
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