Purification, toxicity, and antiendotoxin activity of polymyxin B nonapeptide.

Polymyxin B, a relatively toxic antibiotic, has potent endotoxin-neutralizing properties that may be beneficial as adjunctive therapy in gram-negative sepsis. Polymyxin B nonapeptide (deacylated polymyxin B) is devoid of antibiotic activity but retains the capacity to disorganize the outer membrane...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Danner, R L, Joiner, K A, Rubin, M, Patterson, W H, Johnson, N, Ayers, K M, Parrillo, J E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172678/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.9.1428
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