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How important are entropic contributions to enzyme catalysis?

The idea that enzymes accelerate their reactions by entropic effects has played a major role in many prominent proposals about the origin of enzyme catalysis. This idea implies that the binding to an enzyme active site freezes the motion of the reacting fragments and eliminates their entropic contri...

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Detalles Bibliográficos
Autores principales: Villà, J., Štrajbl, M., Glennon, T. M., Sham, Y. Y., Chu, Z. T., Warshel, A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC17266/
https://ncbi.nlm.nih.gov/pubmed/11050223
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