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Cross-resistance to fluoroquinolones in multiple-antibiotic-resistant (Mar) Escherichia coli selected by tetracycline or chloramphenicol: decreased drug accumulation associated with membrane changes in addition to OmpF reduction.

Chromosomal multiple-antibiotic-resistant (Mar) mutants of Escherichia coli, selected on agar containing low concentrations of tetracycline or chloramphenicol, were 6- to 18-fold less susceptible to the fluoroquinolones than were their wild-type E. coli K-12 or E. coli C parental strains. The freque...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Cohen, S P, McMurry, L M, Hooper, D C, Wolfson, J S, Levy, S B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172647/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2679373/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.8.1318
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