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Determinants of the efficacy of tobramycin therapy against isogenic nonmucoid and mucoid derivatives of Pseudomonas aeruginosa PAO1 growing in peritoneal chambers in mice.

Mice which were supporting the growth of Pseudomonas aeruginosa in chambers implanted in their peritoneums were given two intramuscular injections of tobramycin (15 mg/kg of body weight each) at an interval of 8 h. Three hours later, chambers were removed and their contents were assessed for viable...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Kelly, N M, Rawling, E G, Hancock, R E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172626/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2508542/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.8.1207
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