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Efficacy of dicloxacillin-coated polyurethane catheters in preventing subcutaneous Staphylococcus aureus infection in mice.

In a mouse model, dicloxacillin-coated polyurethane catheters or control (uncoated) catheters were placed subcutaneously and then Staphylococcus aureus was inoculated at the time of insertion, 24 or 48 h later. The in vivo half-life of the antibiotic was 11 to 16 h. When 10(5) CFU of S. aureus were...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Sherertz, R J, Forman, D M, Solomon, D D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2802545/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.8.1174
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