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Comparative pharmacokinetics of clarithromycin (TE-031), a new macrolide antibiotic, and erythromycin in rats.

Clarithromycin (TE-031) is a newly synthesized macrolide with high stability in acidic conditions. In the present study, the pharmacokinetics of [N-methyl-14C]clarithromycin were compared with those of [N-methyl-14C]erythromycin in rats by radioassay and bioassay. Both radioactivity and bioactivity...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Kohno, Y, Yoshida, H, Suwa, T, Suga, T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172527/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2526615/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.5.751
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