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Comparative evaluation of daptomycin (LY146032) and vancomycin in the treatment of experimental methicillin-resistant Staphylococcus aureus osteomyelitis in rabbits.

A rabbit model for methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis was used to compare treatment with daptomycin, a new peptolide, and vancomycin. Daptomycin (4 mg/kg) and vancomycin (40 mg/kg) were injected subcutaneously every 12 and 6 h, respectively. After treatment, MRSA was fo...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Mader, J T, Adams, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1989
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172515/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2546488/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.5.689
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