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In vitro bone marrow toxicity of nucleoside analogs against human immunodeficiency virus.

3'-Azido-2',3'-dideoxythymidine is known to cause severe anemia and neutropenia. Although these are rare for 2',3'-dideoxycytidine, it frequently impairs thrombocytogenesis. These differential myelossuppressive features correlated well with the in vitro toxicities of the drugs for a megakaryoblastic...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Inoue, T, Tsushita, K, Itoh, T, Ogura, M, Hotta, T, Saneyoshi, M, Yoshida, S, Saitoh, H, Tomoda, Y, Nagai, Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1989
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172483/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543285/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.4.576
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