Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin

Nitric oxide (NO) induces vasodilatatory, antiaggregatory, and antiproliferative effects in vitro. To delineate potential beneficial effects of NO in preventing vascular disease in vivo, we generated transgenic mice overexpressing human erythropoietin. These animals induce polyglobulia known to be a...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ruschitzka, Frank T., Wenger, Roland H., Stallmach, Thomas, Quaschning, Thomas, de Wit, Cor, Wagner, Klaus, Labugger, Ralf, Kelm, Malte, Noll, Georg, Rülicke, Thomas, Shaw, Sidney, Lindberg, Raija L. P., Rodenwaldt, Barbara, Lutz, Hans, Bauer, Christian, Lüscher, Thomas F., Gassmann, Max
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027359/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.21.11609
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