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Susceptibility of Giardia lamblia to aminoglycoside protein synthesis inhibitors: correlation with rRNA structure.

The very limited development of antiparasitic agents targeting protein synthesis stems in part from the belief that parasite and host ribosomes are sufficiently similar to preclude selective toxicity. However, recent studies have revealed that Giardia lamblia rRNA has an unusual size and sequence; c...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autor: Edlind, T D
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172465/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2729943/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.4.484
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