In vivo efficacy of zidovudine (3'-azido-3'-deoxythymidine) in experimental gram-negative-bacterial infections.

The therapeutic efficacy of orally administered zidovuldine (3'-azido-3'-deoxythymidine) was determined in animals infected with Escherichia coli and Salmonella dublin. The 50% effective dose (ED50) of zidovudine (9.6 to 11.8 mg/kg of body weight) compared favorably with that of trimethoprim (19.4 t...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Εκδόθηκε σε:	Antimicrob Agents Chemother
Κύριοι συγγραφείς:	Keith, B R, White, G, Wilson, H R
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 1989
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172464/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2658792/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.4.479
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