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Influence of antibiotic dose, dosing interval, and duration of therapy on outcome in experimental pneumococcal meningitis in rabbits.

We examined the influence of several pharmacokinetic parameters on cure rates in rabbits with experimental pneumococcal meningitis. When the duration of treatment was kept constant, cure rates improved as the individual dose of ampicillin was increased. On the other hand, when four doses of ampicill...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Täuber, M G, Kunz, S, Zak, O, Sande, M A
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172452/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2729936/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.4.418
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