A comparison of ocular melanocyte and uveal melanoma cell invasion and the implication of α1β1, α4β1 and α6β1 integrins

BACKGROUND/AIMS—Posterior uveal melanoma is the most common intraocular tumour in adults, responsible for the death of approximately 35% of patients. Hepatic metastases are most frequent, and once diagnosed survival is usually less than 1 year. The β1 family of integrins, αvβ3 and MMP-2 and MMP-9 ha...

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Autori principali: Elshaw, S., Sisley, K., Cross, N., Murray, A., MacNeil, S., Wagner, M., Nichols, C., Rennie, I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Original articles - Laboratory science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1723995/
https://ncbi.nlm.nih.gov/pubmed/11371496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjo.85.6.732
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