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Endogenous active efflux of norfloxacin in susceptible Escherichia coli.

Escherichia coli was shown to have an energy-dependent reduced uptake of the fluoroquinolone antimicrobial agent norfloxacin. Studies of everted inner membrane vesicles suggested that this reduced accumulation involved a carrier-mediated norfloxacin active efflux generated by proton motive force wit...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Cohen, S P, Hooper, D C, Wolfson, J S, Souza, K S, McMurry, L M, Levy, S B
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1988
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172374/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3056253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.8.1187
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