Phosphonylmethoxyethyl purine derivatives, a new class of anti-human immunodeficiency virus agents.

A study of the structure-activity relationship of a series of newly synthesized phosphonylmethoxyalkyl purine and pyrimidine derivatives revealed that several adenine derivatives substituted at the N9 position by a 2-phosphonylmethoxyethyl (PME) group inhibited human immunodeficiency virus (HIV)-ind...

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Main Authors: Pauwels, R, Balzarini, J, Schols, D, Baba, M, Desmyter, J, Rosenberg, I, Holy, A, De Clercq, E
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC172337/
https://ncbi.nlm.nih.gov/pubmed/2847636
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