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Histone H2A-mediated transient cytokine gene delivery induces efficient antitumor responses in murine neuroblastoma

A major goal of cancer immunotherapy is the induction of a cell-mediated antitumor response in poorly immunogenic malignancies. We tested the hypothesis that this can be achieved by cytokine gene therapy with a novel histone H2A-based transient transfection procedure. This was tested by using cytoki...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Balicki, Danuta, Reisfeld, Ralph A., Pertl, Ursula, Beutler, Ernest, Lode, Holger N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17229/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11016973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.210382997
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