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Expression patterns of cyclin D1 and related proteins regulating G1-S phase transition in uveal melanoma and retinoblastoma

BACKGROUND/AIMS—A checkpoint mechanism in late G1, whose regulation via loss of retinoblastoma protein (pRB) or p16, or overexpression of cyclin D1 or cyclin dependent kinase 4 (CDK4), has been proposed to constitute a common pathway to malignancy. The aims of this study were (a) to compare markers...

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Bibliografische gegevens
Hoofdauteurs: Coupland, S, Bechrakis, N, Schuler, A, Anagnostopoulos, I, Hummel, M, Bornfeld, N, Stein, H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1722705/
https://ncbi.nlm.nih.gov/pubmed/9828785
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