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Pharmacokinetics of imipenem-cilastatin in patients with renal insufficiency undergoing continuous ambulatory peritoneal dialysis.

In six patients with end-stage renal disease, a single bolus of imipenem-cilastatin (500 mg each) was given either intravenously or intraperitoneally in a randomized crossover protocol such that each patient received the drug by both routes at a 2- to 3-week interval. Drug levels in plasma and the p...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Somani, P, Freimer, E H, Gross, M L, Higgins, J T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172215/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3377464/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.4.530
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