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Pharmacokinetics of cefoperazone (2.0 g) and sulbactam (1.0 g) coadministered to subjects with normal renal function, patients with decreased renal function, and patients with end-stage renal disease on hemodialysis.

The single-dose pharmacokinetics of intravenously administered cefoperazone (2.0 g) and sulbactam (1.0 g) were studied in normal subjects and in patients with various degrees of renal failure. In an open, parallel experimental design, six normal subjects (creatinine clearance, greater than 90 ml/min...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Reitberg, D P, Marble, D A, Schultz, R W, Whall, T J, Schentag, J J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172210/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3377461/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.4.503
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