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Immunization against Alzheimer's β-amyloid plaques via EFRH phage administration
The epitope EFRH, corresponding to amino acids 3–6 within the human β-amyloid peptide (AβP), acts as a regulatory site controlling both the formation and disaggregation process of the β-amyloid fibrils (Aβ). Locking of this epitope by highly specific antibodies affects the dynamics of the entire AβP...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC17221/ https://ncbi.nlm.nih.gov/pubmed/11027345 |
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