Genetic susceptibility to breast cancer: HLA DQB*03032 and HLA DRB1*11 may represent protective alleles

Tumors are believed to emerge only when immune surveillance fails. We wished to ascertain whether the failure to inherit putative protective alleles of HLA class II genes is linked to the development of breast cancer. We molecularly typed HLA DPB1, DQB1, DRB1, and DRB3 alleles in 176 Caucasian women...

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Autores principales: Chaudhuri, Subhra, Cariappa, Annaiah, Tang, Mei, Bell, Daphne, Haber, Daniel A., Isselbacher, Kurt J., Finkelstein, Dianne, Forcione, David, Pillai, Shiv
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC17220/
https://ncbi.nlm.nih.gov/pubmed/11027344
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