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Antiherpesvirus activity of 9-(4-hydroxy-3-hydroxymethylbut-1-yl) guanine (BRL 39123) in animals.

The antiviral activity of 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine (BRL 39123) was assessed in several animal models of herpes simplex virus (HSV) infection. BRL 39123 was as active as acyclovir (ACV) when applied topically to guinea pigs with a cutaneous HSV type 1 (HSV-1) infection and was als...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Boyd, M R, Bacon, T H, Sutton, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172176/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3364954/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.3.358
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