Effect of protein binding on serum bactericidal activities of ceftazidime and cefoperazone in healthy volunteers.

The effect of protein binding on antibiotic efficacy is controversial. The pharmacologic effect of an antibiotic is believed to be related to its unbound concentration at the site of infection. It is unknown whether antibiotics with a low degree of serum protein binding are clinically superior to an...

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Hlavní autoři: Lam, Y W, Duroux, M H, Gambertoglio, J G, Barriere, S L, Guglielmo, B J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1988
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC172163/
https://ncbi.nlm.nih.gov/pubmed/3284457
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