Purification of Citrobacter freundii DNA gyrase and inhibition by quinolones.

DNA gyrase is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA. It is the accepted target of quinolones. The enzyme from Citrobacter freundii IID976 was purified by affinity chromatography on novobiocin-Sepharose and heparin-Sepharose. It had two subunits, designated...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Aoyama, H, Sato, K, Fujii, T, Fujimaki, K, Inoue, M, Mitsuhashi, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2831810/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.1.104
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