LY146032, alone and in combination with gentamicin, for the treatment of enterococcal pyelonephritis in the rat model.

The in vivo and in vitro activity of LY146032 against Streptococcus faecalis GK was examined. The following MICs and MBCs in micrograms per milliliter were obtained: ampicillin, 0.8 and 1.5; vancomycin, 0.8 and 50; gentamicin, 12 and 25; and LY146032, 0.8 and 6. A time-kill-curve study involving app...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Sapico, F L, Ginunas, V J, Canawati, H N, Montgomerie, J Z
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1988
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172103/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2831816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.1.81
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